DNA Binding Motif

						

			
Accessions: HOXD12_EOMES_2_3 (HumanTF2 1.0)

			
Names: HOXD12_EOMES
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 14
Consensus: TmrCACcTCrTwAA
Weblogo: 
PSSM: P0      A      C      G      T
01    850    546    306   7794      T
02   2452   5343   1129    711      m
03   5101    922   2348    547      r
04    225   8054     71    150      C
05   7120    132   1542    310      A
06    575   7619   1359      9      C
07   2961   6937   2224    328      c
08     28   1779    256   7421      T
09   2000   7565    822    323      C
10   3419    517   4150    428      r
11     87     92     36   8060      T
12   4493    295     78   3591      w
13   7920      0    216    385      A
14   7443   1321    463   1657      A
Type: Heterodimer
Binding TFs: EOMES_TF2 (T-box)
HOXD12_TF1 (Homeobox domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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