DNA Binding Motif

Accessions: TEAD4_FLI1 (HumanTF2 1.0)
Names: TEAD4_FLI1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 12
Consensus: ACCGGAAATrCc
Weblogo:
PSSM: P0 A C G T
01 175 15 23 0 A
02 40 199 20 0 C
03 23 199 17 0 C
04 0 24 199 0 G
05 6 25 199 31 G
06 199 0 5 0 A
07 199 36 15 10 A
08 199 4 37 0 A
09 2 3 0 199 T
10 60 1 139 31 r
11 11 165 34 1 C
12 51 144 0 55 c
Type: Heterodimer
Binding TFs: FLI1_TF2 (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
FLI1_Full (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
TEAD4_TF1 (TEA/ATTS domain family)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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